Editorial Commentary: Galactomannan Testing During Mold-Active Prophylaxis

Editorial Commentary: Galactomannan Testing During Mold-Active Prophylaxis

Choosing a prophylactic approach is a strategic decision impacting the choice, timing, and even the indication of in vitro diagnostic tests and antifungal treatments. In the past, clinical studies informing clinical decisions were conducted in settings without prophylaxis. One may object, that empiric antifungal treatment trials allowed enrolling patients on antifungal prophylaxis with fluconaz...

editorial commentary: prophylaxis for surgical site infections

Editorial Commentary: Prophylaxis for Surgical Site Infections

Despite many attempts to prevent surgical site infections (SSIs), these complications are not uncommon in most hospitals while the precise determination of the burden of these infections in our country has not been performed but crude data in hospitals shows a significant cost of managements. With an estimated 27 million surgical procedures annually, and near 2– 5% rate of SSIs, approximately 3...

Editorial Commentary

Socioeconomic status (SES) is a known risk factor for cardiovascular disease.1,2 However, unlike traditional Framingham risk factors, SES does not directly impact the cardiovascular system but exerts its cardiovascular effects via a complex interaction of biobehavioral factors, such as exercise and diet (Figure). Because these mediating behavioral factors are potentially modifiable, elucidating...

Editorial Commentary: Microbiologic Testing in Post–Solid Organ Transplant Diarrhea

Up to 27% of recipients of solid organ transplant (SOT) experience diarrhea posttransplant, with some episodes being severe enough to require hospitalization [1–3]. Immunosuppressive medications are a common cause, but reduction of immunosuppression carries the risk of allograft rejection, making it necessary to rule out other causes, such as infection, before modifying the immunosuppressive re...